How Are Peptides Made?

Peptides are made by joining amino acids together using a special bond called a peptide bond. This bond is formed when the amino group (–NH₂) of one amino acid combines with the carboxyl group (–COOH) of another amino acid, releasing a molecule of water.

Each amino acid has a central carbon atom, surrounded by:

• A hydrogen atom (H)
• An amino group (–NH₂)
• A carboxyl group (–COOH)
• A unique side chain group (called the R group) that gives each amino acid its own characteristics.

Sometimes, these R groups can interfere with the process of joining the amino acids, so they need to be temporarily protected with special chemical groups until the peptide chain is complete.

How are peptides made in a lab?

In laboratories, peptides are typically made using a method called solid-phase peptide synthesis. Here’s how it works:

1. Starting the Process: The first amino acid is attached to a solid support (a resin) to keep it in place, and its amino group is protected.
2. Adding More Amino Acids: The protective group is removed, allowing the next amino acid to be added. This amino acid forms a peptide bond with the first one.
3. Repeating the Process: The process is repeated, adding one amino acid at a time until the entire peptide chain is created.

Once all the amino acids are in place, the peptide is carefully removed from the solid support. A special acid is used to break the bond between the peptide and the solid support, and it also removes any remaining protective groups on the amino acids.

This step-by-step process allows scientists to create peptides with specific sequences of amino acids for use in research, medicine, or other applications.

At the checkout, you will be asked which payment method you would like to use.

Bank Transfer

It is simple to make a bank transfer with your online banking or mobile banking app, or you can also make the transfer in a branch.

Please ensure you confirm your order.

Please note: If you pay into our account using another person’s bank account, such as your partner’s or friend’s account, please get in touch with us and tell us the name of the bank account and your order ID number to avoid any delays in postage times.

Cryptocurrency

Once you confirm your order, a pop-up screen with a QR code should appear. Use this to make the payment or use the wallet address. This process will usually take an hour before the order is confirmed; in some occasions, this can be longer. If your screen has timed out, don’t worry; our system will complete the order once the payment has been successful.

Card Payment By Link

UK customers: Once you have confirmed your order, we will manually create your unique link, which we will email to you. If you have made the order outside working hours, we will process your link on the next working day.

International customers: You can process the order once you have confirmed it.